Susana Lopes, CEDOC researcher and Co-Coordinator of LYSOCIL, wins prémio Maratona da Saúde
Susana Lopes, Principal Investigator of the cilia regulation and disease laboratory at CEDOC-NMS, won the prestigious Maratona da Saúde award in biomedical research. It's going to allow research in primary ciliary dyskinesia (pcd), a rare disease studied by Susana's group.
In partnership with RTP+, Maratona da Saúde combines science with entertainment through an annual solidarity, which aims to encourage the involvement of the Portuguese in health issues and raise donations to fund excellent scientific research carried out in Portugal.
"This award will allow you to make more models of Primary Ciliary Dyskinesia disease in zebrafish and test their messenger RNA therapy. We had promising results (not yet published) with the first model for the CCDC40 protein. The disease in question will need a specialized therapy for each mutated gene, until now we had only one animal model for a protein, the one that causes a more severe disease" says Susana Lopes. "With the Maratona da Saúde award we will make a specific model for proteins that most frequently cause Primary Ciliary Dyskinesia disease such as DNAH5".
See the Interview here at RTP1 (minute 41)
Please note that this video is only available in Portuguese.
Highlights

New edition of the Research Topic “The Cytoskeleton and Cellular Compartmentation: Cilia as Specialized Cellular Domains” | Frontiers Journal

Honorable Mention Award of the contest “Science on Stage at the University” - video “escleROdeRmiA: when RARE is not obvious”

LYSOCIL LIG session dedicated to “Alzheimer’s mutation in CD2AP increases intracellular beta-amyloid by reducing APP endosomal sorting”

LYSOCIL LIG session dedicated to “Uncoupling heart and liver laterality events during embryogenesis”

LIG session dedicated to “Lysosome turnover in the retinal pigment epithelium in health, ageing and age-related macular degeneration”
LYSOCIL Coordinator is the new member of the Scientific Council of the Sanfilippo Association in Portugal
Virtual Think Tank (VTT) session dedicated to “The scientific review on the state-of-the-art of the lysosome, cilia and autophagy connection”
Virtual Think Tank (VTT) session dedicated to “Gene Editing as rare disease therapy – main challenges and alternatives”