LYSOCIL: Excel in Rare Diseases’ Research: Focus on LYSOsomal Disorders and CILiopathiesis a H2020 Twinning Project led by NOVA Medical School (NMS) that aims to strengthen the research and innovation capacity of the Chronic Diseases Research Center (CEDOC-NMS|FCM), helping it to become a national and internationally-recognized Centre of Excellence in Chronic rare diseases research and innovation.

HIGHLIGHTS

LYSOCIL CEDOC-NMS I FCM special seminar with Guillaume Van Niel

LYSOCIL CEDOC-NMS I FCM special seminar with Oliver Blacque

LYSOCIL LIG session dedicated to “Alzheimer’s mutation in CD2AP increases intracellular beta-amyloid by reducing APP endosomal sorting”

LYSOCIL CEDOC-NMS I FCM special seminar with Antonio Cuadrado

LYSOCIL CEDOC-NMS I FCM special seminar with Patricia Boya

LYSOCIL LIG session dedicated to “Uncoupling heart and liver laterality events during embryogenesis”

Rare Diseases Day

LIG session dedicated to “The impact of BIN1 mutants on Alzheimer's Disease cellular pathology”

LYSOCIL CEDOC-NMS I FCM special seminar with Christopher Westlake

LIG session dedicated to “Lysosome turnover in the retinal pigment epithelium in health, ageing and age-related macular degeneration”

LYSOCIL Winter Retreat 2021

LYSOCIL CEDOC-NMS I FCM special seminar with Kerem Pekkan

LYSOCIL Coordinator is the new member of the Scientific Council of the Sanfilippo Association in Portugal

Retina Interest Group – 2nd Virtual Meeting

Purification and characterization of dysfunctional lysosomes in chronic age-related disease models

Virtual Think Tank (VTT) session dedicated to “Methods to analyze lysosomes”

“Semana da Ciência e Tecnologia”

Virtual Think Tank (VTT) session dedicated to “The scientific review on the state-of-the-art of the lysosome, cilia and autophagy connection”

LIG session dedicated to "Up-regulation of APP endocytosis by neuronal aging"

“Dia Solidário” of Maratona da Saúde on RTP1 and RTP Internacional

Retina Interest Group

Staff Exchange on “Training in transferable skills”

LIG session dedicated to 'Different cellular responses to lysosome dysfunction'

Virtual Think Tank (VTT) session dedicated to “Gene Editing as rare disease therapy – main challenges and alternatives”

LIG session dedicated to "Deciphering the molecular mechanisms of skin pigmentation"

LIG session dedicated to "The Extracellular Vesicles in the zebrafish left-right axis development"

Second LIG session dedicated to 'Modelling retinal degenerative diseases using 3D retinal organoids'

LYSOCIL Interest Group sessions

Informative Guide for People with Rare Disease and their Caregivers

Clinical trials reveal the efficacy of hydroxychloroquine in treating COVID-19

OPEN DAY CEDOC-LYSOCIL 2020

LYSOCIL Winter Retreat and “Best Project idea” competition

Staff Exchange “Training on the analysis of lysosome morphological changes”

Workshop Lysosome Biology

Staff Exchanges in “Induced pluripotent stem cell (iPSC) and in Immunostainings”

Staff Exchange “Research funding offices capacity building”

Workshop on Outreach & Fundraising

LYSOCIL Kick-off Meeting